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chemical mapping
Recent advances in a number of chemical spectroscopy techniques allows for fast acquisition of spatially resolved chemical spectra. Careful interpretation and reconstruction of this data can provide information rich chemical maps with a spatial resolution down to 350nm and where possible 3D chemical maps. For formulated drug delivery systems the ability to chemically identify the distribution of components can be valuable for resolving issues related to unexpected drug release profiles, stability testing and batch to batch variation. |
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• ToF-SIMS (Time-of-Flight
Secondary Ion Mass Spectrometry)
• XPS (X-ray Photoelectron
Spectroscopy)
• (Micro Attenuated Total
Reflectance FTIR)
• Infrared Microscopy
• CRM (Confocal Raman Microscopy)
• SThM (Scanning Thermal Microscopy)
• EDAX (Energy Dispersive Analysis
by X-ray) |
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