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inhalation
The ability to predict and control the complex interplay of forces that can predominate within an inhaled formulation is valuable in expediting the development of an active into a viable and reproducible formulation.
With milligram levels of API, we can provide detailed analytical reports covering the assessment of bulk and surface physicochemical properties. Interactions in context to formulation components, device materials and packaging systems can be routinely quantified as a function of solution, humidity and thermal conditioning.
Types of analysis include:
• Particle size and shape distribution
• Surface morphology / roughness at µm &
nm scale
• Spatially resolved surface chemistry & structural composition
• Relative cohesive strength of drug-to-drug and adhesive strength of drug-to-carrier particles and particles to packaging surfaces
• Quantified analysis of surface modified systems
• Identification of component migration / segregation & contamination |
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